despondencen.

despondence (n.)1670s, from Latin despondere "to give up, lose, lose heart, resign, to promise in marriage" (especially in phrase animam despondere, literally "give up one\\'s soul"), from the sense of a promise to give something away, from de- "away" (see de-) + spondere "to promise" (see spondee). A condition more severe than despair.